1. Overview Guidelines for Chemical Process Quantitative Risk Analysis is a seminal technical reference published by the Center for Chemical Process Safety (CCPS) of the American Institute of Chemical Engineers (AIChE). First released in 1989 (with subsequent editions, e.g., 2nd edition 2000, and updates integrated into other CCPS guidelines), this document provides a systematic, rigorous methodology for identifying, evaluating, and managing risks associated with chemical process hazards.